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Vol. 1, No. 10, 17 September 2001
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AIDScience Perspective:
National Institutes of Health AIDS research priorities and funding
By Jack Whitescarver, Wendy J. Wertheimer, and Robert W. Eisinger.
This article describes major HIV/AIDS research programs at U.S. National Institutes of Health, as well as increases for those programs requested by President Bush. The U.S. Congress has not yet passed the bill that will fund this agency from October 1, 2001, to September 30, 2002 (Appropriations for the Departments of Labor, Health and Human Services, Education, and related Agencies).
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Hot News:
National Minority AIDS Council cancels 5th U.S. Conference on AIDS
The 5th U.S. Conference on AIDS, scheduled for September 13-16 in Miami Beach, Florida, has been cancelled, due to transportation problems caused by the shutdown of air travel following terrorist attacks on New York City and Washington.
[Go to NMAC site]
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American Society for Microbiology postpones ICAAC
The 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) originally scheduled in Chicago, September 22-25, has been rescheduled for December 16-19, 2001, also in Chicago.
[Go to ICAAC site]
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U.S. $2.5 million enough to reduce HIV infection of world's babies
The 3rd International Conference on Global Strategies for Prevention of Mother-to-Infant HIV Transmission, attended by 700 experts from 52 countries, ended by issuing a "call to action." It would cost just U.S. $2.5 million worth of drugs to significantly reduce HIV infection of unborn babies across the world, a statement said.
[Read news in AllAfrica.com] [Go to conference site]
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Compendium of HIV prevention interventions with evidence of effectiveness
From CDC's HIV/AIDS Prevention Research Synthesis Project, November 1999, Revised. This document has been revised and is accessible now from the CDC — National Center for HIV, STD and TB Prevention — Division of HIV/AIDS Prevention Web site.
[Go to site]
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From Medscape: Selected Highlights from the 7th Annual Conference of the British HIV Association
Read brief, very selective summaries of this conference in The AIDS Reader.
The AIDS Reader 11(6):299-302,316, 2001
[Go to Medscape]
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Science Classic Papers:
Selective transcription and modulation of resting T cell activity by preintegrated HIV DNA
Yuntao Wu and Jon W. Marsh, Science 293(5534):1503-1506, 24 August 2001.
A new unexpected step in the process that HIV uses to infect human cells has been discovered. Most CD4+ T cells, in which HIV replicates predominantly, exist in a resting state that resists HIV infection. But in a new Science article researchers at the U.S. National Institute of Mental Health show that after reverse transcription of its RNA and before the integration of the viral DNA into the cellular DNA, the HIV DNA serves as a template to make the viral proteins Nef and Tat. This preintegration transcription in quiescent cells leads to increased T cell activation and viral replication.
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dEbates: Readers' online reactions
Do you disagree with an article or opinion? Submit a response or commentary to any article published in AIDScience. Let your opinion count.
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