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Vol. 3, No. 5, 14 March 2003
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Other Issues:
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AIDScience Perspective:
Neutralizing antibody response to HIV and virus escape. Despite an early and effective neutralizing antibody defense, initial infecting viruses are able to mutate rapidly into resistant viruses, escaping neutralization by antibodies.
By Roberto Fernandez-Larsson.
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From Science:
CLINICAL RESEARCH:
AIDS vaccine results draw investor lawsuits. VaxGen, the Brisbane, California, biotech that came under scientific fire last month when it revealed results of the first-ever real-world trial of an AIDS vaccine, is now dodging legal bullets.
By Jon Cohen.
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Hot News:
HIV in central and eastern Europe. During the past 5 years, most countries of the former Soviet Union have been severely affected by HIV epidemics that continue to spread as a result of injecting drug use. Eastern Europe will soon be confronted with a major AIDS epidemic.
Lancet, 361, 1035, 22 March, 2003 [Read article]
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Neutralizing antibody response and virus escape. Two papers examine how antibodies quickly eliminate neutralization-sensitive HIV in early infection, only to be replaced by populations of resistant virus. One of the teams discovered that the glycan moieties of env change — rather than protein epitopes — in yet another mechanism of viral escape.
Nature 422, 307, 20 March 2003 [Read abstract]
Proc. Natl. Acad. Sci. USA, published online 18 March, 2003 [Read abstract]
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Latest News Headlines:
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U.S. clears novel AIDS drug from Roche, Trimeris. Yahoo! News. March 14, 2003
| New AIDS drug spurs anxiety, anger, hope. New York Times. March 14, 2003
| VaxGen stock soars on improved forecast. New York Times. March 14, 2003
| New AIDS drug price spurs questions. The Nando Times. March 13, 2003
| Uganda leads by example on AIDS. Washington Times. March 13, 2003
| WHO hopes to double AIDS treatment in Latin America. Yahoo! News. March 13, 2003
| VaxGen to present update. VaxGen release. March 13, 2003
| Satellite broadcast on HIV prevention. Morbidity and Mortality Weekly Report. March 13, 2003
| Trial: Glaxo AIDS drug less effective than others. Yahoo! News. March 12, 2003
| Report: HIV prevalence in South African jails could be over 45%. AllAfrica.com. March 12, 2003
| amfAR awards grants for new HIV/AIDS research. amfAR release. March 12, 2003
| South Africa appoints consultant who rules out AIDS/HIV link. Guardian. March 11, 2003
| Thailand gets U.S.$209 million to fight illnesses. Bangkok Post. March 11, 2003
| National Minority AIDS Council hosts HIV/AIDS training for AIDS groups. AIDScience. March 11, 2003
| HIV lessons used in hepatitis C treatment. New York Times. March 11, 2003
| California court dismisses AIDS Healthcare Foundation lawsuit. Yahoo! Finance. March 11, 2003
| Thailand to host next global fund meeting on diseases. Bangkok Post. March 10, 2003
| Chinese AIDS group lobbies parliament on orphans. Reuters Health. March 10, 2003
| South Africa stalls again on access to HIV drugs. Lancet news. March 10, 2003
| Charity decisions tough, necessary. Yahoo! News. March 8, 2003
| Advocate adamant V-1 study legitimate. Bangkok Post. March 6, 2003
| Politics of abortion delays $15 billion to fight global AIDS. New York Times. March 6, 2003
| Black life expectancy in Cape Town drops as AIDS takes hold. Yahoo! News. March 6, 2003
| Spread of AIDS in Africa driven by poor medical practice, says report. BMJ News. March 6, 2003
| The politics of AIDS in South Africa: beyond the controversies. BMJ Debate. March 6, 2003
| USAID plans probe of AIDS research. Washington Times. March 5, 2003
| Sweden considers needle-exchange for drug users. Reuters Health. March 5, 2003
| Malarial treatment for Chinese AIDS patients prompts inquiry in U.S.. New York Times. March 4, 2003
| AIDS takes toll on African militaries. Washington Post. March 4, 2003
| Can AID be beaten?. The Independent. March 3, 2003
| Stirring up racial concerns. San Francisco Chronicle. March 3, 2003
| Next on AIDS' frontier. Los Angeles Times. March 3, 2003
| A plan as simple as ABC (opinion). New York Times. March 2, 2003
| Race, sex and stigmas (opinion). New York Times. March 2, 2003
| Prosperous Taiwan fights HIV with education. San Francisco Chronicle. March 1, 2003
| Newspapers, magazines commit to devoting space to AIDS epidemic in black community. San Francisco Chronicle. March 1, 2003
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More news headlines: This week | Last week | Search archive |
Latest Journal Headlines:
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| Enfuvirtide,an HIV-1 Fusion Inhibitor, for Drug-Resistant HIV Infection. New England Journal of Medicine. (Posted: March 14, 2003) | | Effective cross-clade neutralization with mAbs raised against clade B. AIDS Research and Human Retroviruses. (Posted: March 10, 2003) | | A new perspective on V3 phenotype prediction. AIDS Research and Human Retroviruses. (Posted: March 10, 2003) | | Overcoming barriers to HIV testing. Journal of Acquired Immune Deficiency Syndromes. (Posted: March 10, 2003) | | NeuroAIDS: Increased intrathecal release of soluble fractalkine in HIV-infected patients. AIDS Research and Human Retroviruses. (Posted: March 10, 2003) | | Characterization and selection of HIV-1 subtype C isolates for use in vaccine development. AIDS Research and Human Retroviruses. (Posted: March 10, 2003) | | Assessing the magnitude of the HIV/AIDS epidemic in Burma. Journal of Acquired Immune Deficiency Syndromes. (Posted: March 10, 2003) | | Need for a true placebo for vaginal microbicide efficacy trials. Lancet. (Posted: March 6, 2003) | | Potential role for CD63 in CCR5-mediated HIV-1 infection of macrophages. Journal of Virology. (Posted: March 6, 2003) | | Effect of amino acid substitution of the V3 and bridging sheet residues on CCR5 utilization. Journal of Virology. (Posted: March 6, 2003) | | Human immunodeficiency virus type 1 infection and replication in normal human oral keratinocytes. Journal of Virology. (Posted: March 6, 2003) | | The CD8+ cell noncytotoxic anti-HIV response can be blocked by protease inhibitors. Proc. Natl. Acad. Sci. USA. (Posted: March 6, 2003) | | Enhancement of mucosal immunization with virus-like particles of simian immunodeficiency virus. Journal of Virology. (Posted: March 6, 2003) | | Variability in the incidence of HIV, HBV, and HCV infection among young ID users in New York City. American Journal of Epidemiology. (Posted: March 6, 2003) | | A multicenter trial to reduce intrapartum and early postpartum mother-to-child transmission. Journal of Infectious Diseases. (Posted: March 6, 2003) | | Natural alpha IFN-producing cells respond to HIV-1 with alpha IFN production and maturation into DCs. Journal of Virology. (Posted: March 6, 2003) | | NeuroAIDS: TNF-related apoptosis-inducing ligand induces neuronal death in a murine model of HIV CNS infection. Proc. Natl. Acad. Sci. USA. (Posted: March 6, 2003) | | Candidate HIV/AIDS vaccines: Lessons learned from the world's first phase III efficacy trials. AIDS. (Posted: March 4, 2003) | | HIV, ethnicity and travel: HIV infection in Vietnamese Australians associated with ID use. Journal of Clinical Virology. (Posted: March 2, 2003) |
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